Sunday, September 27, 2015

DAO, MAO a and Histimine Intolerance, "say what?"


Ahhhhh…. I want to fist start out by saying how grateful I am for the people and the support I have in my life and all the positive things that have happened over the past several months.
What Hives Look Like, otherwise known as Uticaria. ITCHY!!

As you may or may not know the last several months have not been free of stress and were in fact some of the more stressful in my life. It turns out I created the perfect storm for turning on a couple of genetic mutations that are homozygous, which has resulted in histamine intolerance, which is more common in women over the age of 40. The genes are DAO and MAOa in addition to others that aren’t contributing in a positive manner. So what does all this mean? It means that foods I thought were very healthy for me are suddenly causing my body to be overloaded with histamine and causing hives almost every evening. I can count the days I haven’t had them on one hand and it also means the occasional bout of allergic conjunctivitis among being a contributor to many other symptoms. I will tell you this is similar to a CBS mutation in that I need to make every effort to lower my histamine load in order to get the symptoms under control and then I may be able to have some problem foods from time to time. I do have hope that there is a solution, but I have suddenly found myself feeling sucked into the “oh poor me” attitude or maybe not so much “oh poor me” as just feeling like my chronic issues are a ball and chain that I’m constantly caring around. I just want to feel normal. I don’t really know what normal is anymore.

It’s like a ton of bricks hit me. Just when I thought I was going to be able to start winding down with some of the protocols that I’m on and I was feeling hopeful that I could get back to a more “normal” way of life…Dun, dun, dun…chronic hives hit the stage. Oh joy!!! One more mystery to solve… It such a strong as someone with chronic autoimmune issues that all stresses are a risk it is difficult to tell how the body responds to those stresses. 

Sometimes we fair better than others. I’ve had a couple of pity parties for myself and oh, by the way that is another lovely symptom of these particular genetic mutations… issues with neurotransmitters. Seratonin, norepinepherine…  So my emotions are on a bit of a roller coaster too.
 
Well, stay tuned for the updates. I have high hopes that I can put hives behind me. They are truly maddening.